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Fractures from osteoporosis are more common than breast cancer, stroke, and heart attack combined

Atypical femur fractures (AFFs)

Since the early 2000s, there have been increasing reports regarding a distinctive form of femur (thigh bone) fracture. Being the largest bone in the human body, the femur is naturally resilient and not prone to breaking from minor incidents such as a simple slip and fall from standing height, which are typically referred to as 'low-trauma' or 'low-impact' events. However, bones may succumb to fractures under higher levels of force, such as those encountered in car accidents, sports injuries, or falls from heights like ladders or stairs; these are termed 'high-impact' or 'traumatic' fractures.

Individuals with osteoporosis, characterized by decreased bone density and strength, are particularly susceptible to fractures even from minor incidents like slipping and falling. Traditionally, bones most commonly affected by falls include wrists, spinal vertebrae, and hips. However, recently, there have been emerging accounts of individuals presenting to emergency departments with femur fractures resulting from low-impact falls.

As these cases accumulated, the medical and scientific communities mobilized efforts to investigate these atypical femur fractures, aiming to uncover their underlying causes and develop preventive measures.

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