Currently recruiting control subjects for our study

Atypical femur fractures (AFFs)

For about 10 years, reports have been emerging on a unique type of fracture of the femur (thigh) bone. The femur bone is the largest bone in the human body. As with all our bones, a healthy femur bone is designed not to break from a simple slip and fall from standing height; this is called ‘low-trauma’ or ‘low-impact’ event. Bones may break if they experience some impact like a car accident, sporting injury, fall from a ladder or down stairs; these are called ‘high-impact’ or ‘traumatic’ fractures.



People with osteoporosis have weaker bones and they sometimes break a bone from a low-trauma event, like slipping and falling. The ‘typical’ types of bones that break from a fall are wrists, spine bones (vertebra) and hip bones. Very recently, accounts of people presenting to emergency wards with broken femur bones from low impact falls starting being described.


As more of these stories were related, the medical and scientific community came together to study these atypical femur fractures in an attempt to shed some light on their causes and how to prevent them.

Our Current Studies





Personalizing Osteoporosis Care

The Ankle Fractures and Bone-Muscle Quality Study

Contact Us

585 University Avenue, Norman-Urquhart Building, 7th Floor

University Health Network (UHN)

Toronto General Hospital

North Building, 7th Floor, Room 7N-700

585 University Avenue

Toronto, ON M5G 2N2

+1 (416) 340-4800 x 8049